Joe Schmidt has named his side for Ireland’s Six Nations opener with Scotland.
Iain Henderson gets the nod in the second row ahead of Donnacha Ryan, who is excluded from the matchday 23.
The Ulster lock forms a second row partnership with Devin Toner.
Jack McGrath, Rory Best and Tadhg Furlong make up the front row.
And in the back row, Sean O’Brien is fit to start alongside CJ Stander and Jamie Heaslip.
Andrew Trimble misses out, with Simon Zebo and Keith Earls manning the wings, and Tommy Bowe providing back-up from the bench.
Rob Kearney starts at full-back, with his Leinster team-mates Garry Ringrose and Robbie Henshaw continuing their centre partnership.
As expected, Paddy Jackson starts at out-half, with Conor Murray at scrum-half.
Ian Keatley provides cover for Jackson on the bench.
Schmidt says Sexton has an outside chance of being fit for the trip to Italy, while Peter O’Mahony is highly unlikely to travel to Rome with a hamstring injury.
The head coach is more hopeful as far as Trimble is concerned.