Bundee Aki, Ultan Dillane and Dave Heffernan will all start for Connacht in their Pro14 inter-conference clash with Cardiff Blues at the Sportsground.
Jarrad Butler returns to captain the side from openside flanker, with Eoghan Masterson and Paul Boyle forming the rest of the back row.
Dillane is partnered by Gavin Thornbury in the second row, while Heffernan is joined by props Jordan Duggan and Finlay Bealham to complete the pack.
Duggan will make his first start for the province with his seven previous appearances coming off the bench.
Caolin Blade and Jack Carty start at 9 and 10 respectively, while Bundee Aki forms an exciting centre partnership with Tom Daly.
John Porch continues his run of starting every game this season, forming a back three with wingers Matt Healy and Alex Wootton.
