Permission has been granted for a change of use of the former enterprise centre in Clones.
The works will see the existing enterprise building become a meat processing and packaging facility.
The application, which was lodged by Fayman Europe Limited, says "it is prudent for additional agri-food processing and packaging facilities to be provided" due to Brexit uncertainty.
It adds that Clones' proximity to the border "means the proposal is well-placed to maximise the strategic linkages between the economies of Northern Ireland and the Republic of Ireland".
Among the plans is the change of use of the former enterprise centre to the processing facility.
There is also provision for an electric vehicle charging point, alongside the retention of the existing LPG tanks at the site.
The works were granted by Monaghan County Council, subject to eight conditions, including the need for the odour management and mitigation procedures to be implemented in full.