The N3 between Butlers Bridge and Belturbet at Kilnalack remains closed this morning following a road traffic accident yesterday evening.
The collision claimed the life of a 17-year-old boy and left two others with non-life threatening injuries.
The man, in his 40s, and a women in her 50s are currently being treated at Cavan General Hospital.
Local diversions are in place.
Meanwhile, Gardaí are appealing for witnesses to come forward, particularly those with dash-cam footage.