Emergency services are currently at the scene of a crash in Aughnacloy, close to the Co Monaghan border.
The Tullyvar Road is blocked in both directions following a road traffic collision.
A statement issued by the PSNI to Northern Sound stated: "Road users are advised that the Tullyvar Road in Aughnacloy is currently blocked in both directions following a road traffic collision.
"Traffic is being diverted via the Favour Royal Road. Please avoid the area and seek alternative routes."